Laboratorio di Ecocardiografia - Ecocardiography laboratory - Director. Prof. Giovanni de Simone Laboratorio di Ecocardiografia - Ecocardiography laboratory - Director. Prof. Giovanni de Simone ipertrofia, ipertensione arteriosa, obesità, funzione cardiaca, scompenso cardiaco, trial clinici, hypertrophy, arterial hypertention, obesity, cardiac function, heart failure, clinical trials The Echocardiography Laboratory has been founded on 1985 by Dr. Giovanni de Simone. Since 1990, the lab increased dimensions and activities until the today's setting. In the Federico II University Hospital ( www.unina.it ), a very large Hospital distributed on a huge area, the Echo Lab performs routine echocardiograms for outpatients, and inpatients referred from Clinical Divisions and Departments. Since 1995, the activity of off-line interpretation of clinical echocardiographic studies has been implemented, and today this is one of the main activities, because of the recent acquisition of new and very potent work-stations which can manage echocardiographic recordings on virtually every type of format. The potentiality of these work stations can be further expanded for future needs, being today able to provide every kind of quantitative measurements on Doppler-echocardiography. The Echocardiography Laboratory cooperates with the Echocardiography Laboratory of the Division of Cardiology of New York Presbyterian Hospital - Weill Medical College of Cornell University di New York (Dr. Richard B. Devereux, Director). Director, Dr. Giovanni de Simone, is Member of both Faculties. Il laboratorio è stato fondato nel 1985 dal Prof. Giovanni de Simone. Dal 1990 ad oggi si è rapidamente sviluppato fino alle dimensioni attuali. Dal punto di vista dell'impegno clinico, esso serve attualmente il 30%dei servizi clinici dell'Azienda Ospedaliera Federico II ed è aperto a tutto il territorio. Dal 1995 ad oggi, ha implementato le funzioni di interpretazione off line di studi clinici di diversa provenienza e di lettura di studi ecocardiografici finalizzati alla ricerca scientifica. In questa veste serve da "Core Lab" per trials internazionali sulla regressione dell'ipertrofia ventricolare sinistra. Questa funzione di interpretazione off-line di studi provenienti da altri laboratori si è definitivamente imposta come una delle principali attività, per l'implementazione recente di potentissime work-station che gestiscono studi registrati su videotape o su supporti digitali, consentendo di sviluppare protocolli di misurazione che investono la totalità dei parametri utilizzati nella pratica clinica e nella ricerca scientifica. Il laboratorio e' affiliato con il Laboratorio di Ecocardiografia della Divisione di Cardiologia del New York Presbyterian Hospital - Weill Medical College of Cornell University di New York. Il Prof. Giovanni de Simone e' membro di entrambe le Facolta'. de Simone G, Palmieri V, Koren MJ, Mensah GA, Roman MJ, Devereux RB. Prognostic implications of the compensatory nature of left ventricular mass in arterial hypertension. J Hypertens. 2001 Jan;19(1):119-25. PMID: 11204291 [PubMed - indexed for MEDLINE] 2. Pasanisi F, Contaldo F, de Simone G, Mancini M. Benefits of sustained moderate weight loss in obesity. Nutr Metab Cardiovasc Dis. 2001 Dec;11(6):401-6. Review. PMID: 12055705 [PubMed - indexed for MEDLINE] 3. de Simone G, Palmieri V. Diastolic dysfunction in arterial hypertension. J Clin Hypertens (Greenwich). 2001 Jan-Feb;3(1):22-7. Review. PMID: 11416678 [PubMed - indexed for MEDLINE] 4. Collis T, Devereux RB, Roman MJ, de Simone G, Yeh J, Howard BV, Fabsitz RR, Welty TK. Relations of stroke volume and cardiac output to body composition: the strong heart study. Circulation. 2001 Feb 13;103(6):820-5. PMID: 11171789 [PubMed - indexed for MEDLINE] 5. Celentano A, Palmieri V, Esposito ND, Pietropaolo I, Crivaro M, Mureddu GF, Devereux RB, de Simone G. Inappropriate left ventricular mass in normotensive and hypertensive patients. Am J Cardiol. 2001 Feb 1;87(3):361-3, A10. PMID: 11165981 [PubMed - indexed for MEDLINE] 6. Paolisso G, Tagliamonte MR, Galderisi M, Zito GA, D'Errico A, Marfella R, Carella C, de Divitiis O, Varricchio M. Plasma leptin concentration, insulin sensitivity, and 24-hour ambulatory blood pressure and left ventricular geometry. Am J Hypertens. 2001 Feb;14(2):114-20. PMID: 11243301 [PubMed - indexed for MEDLINE] 7. de Simone G, Parati G. Imaging techniques for non-invasive assessment of coronary heart disease in hypertension: value of an integrated approach. J Hypertens. 2001 Apr;19(4):679-82. Review. No abstract available. PMID: 11330869 [PubMed - indexed for MEDLINE] 8. Verdecchia P, Schillaci G, Reboldi G, de Simone G, Porcellati C. Original articles prognostic value of combined echocardiography and ambulatory blood pressure monitoring in hypertensive patients at low or medium cardiovascular????ê?????¯?°??????4????????????????????????????????4??????? risk. Ital Heart J. 2001 Apr;2(4):287-93. PMID: 11374498 [PubMed - indexed for MEDLINE] 9. Palmieri V, Wachtell K, Gerdts E, Bella JN, Papademetriou V, Tuxen C, Nieminen MS, Dahlof B, de Simone G, Devereux RB. Left ventricular function and hemodynamic features of inappropriate left ventricular hypertrophy in patients with systemic hypertension: the LIFE study. Am Heart J. 2001 May;141(5):784-91. PMID: 11320367 [PubMed - indexed for MEDLINE] 10. D'Andrea A, Caso P, Galderisi M, Di Maggio D, Cicala S, D'Andrea L, Mininni N, Calabro R. Assessment of myocardial response to physical exercise in endurance competitive athletes by pulsed doppler tissue imaging. Am J Cardiol. 2001 May 15;87(10):1226-30; A8. No abstract available. PMID: 11356409 [PubMed - indexed for MEDLINE] 11. Slotwiner DJ, Devereux RB, Schwartz JE, Pickering TG, de Simone G, Roman MJ. Relation of age to left ventricular function and systemic hemodynamics in uncomplicated mild hypertension. Hypertension. 2001 Jun;37(6):1404-9. PMID: 11408385 [PubMed - indexed for MEDLINE] 12. Mureddu GF, Pasanisi F, Palmieri V, Celentano A, Contaldo F, de Simone G. Appropriate or inappropriate left ventricular mass in the presence or absence of prognostically adverse left ventricular hypertrophy. J Hypertens. 2001 Jun;19(6):1113-9. PMID: 11403361 [PubMed - indexed for MEDLINE] 13. Cioffi G, Mureddu G, Cemin C, Russo TE, Pellegrini A, Terrasi F, Stefenelli C, de Simone G. Characterization of post-discharge atrial fibrillation following open-heart surgery in uncomplicated patients referred to an early rehabilitation program. Ital Heart J. 2001 Jul;2(7):519-28. PMID: 11501961 [PubMed - indexed for MEDLINE] 14. Ducceschi V, D'Andrea A, Galderisi M, De Feo M, Limongelli G, Mercurio B, Sarubbi B, Caso P, Cerasuolo F, Cotrufo M. Risk predictors of paroxysmal atrial fibrillation following aortic valve replacement. Ital Heart J. 2001 Jul;2(7):507-12. PMID: 11501959 [PubMed - indexed for MEDLINE] 15. de Simone G, Pasanisi F, C????ê?????¯?°??????4????????????????????????????????4???????ontaldo F. Link of nonhemodynamic factors to hemodynamic determinants of left ventricular hypertrophy. Hypertension. 2001 Jul;38(1):13-8. Review. PMID: 11463753 [PubMed - indexed for MEDLINE] 16. Iarussi D, Caruso A, Galderisi M, Covino FE, Dialetto G, Bossone E, de Divitiis O, Cotrufo M. Association of left ventricular hypertrophy and aortic dilation in patients with acute thoracic aortic dissection. Angiology. 2001 Jul;52(7):447-55. PMID: 11515983 [PubMed - indexed for MEDLINE] 17. de Simone G, Devereux RB, Kimball TR, Roman MJ, Palmieri V, Celentano A, Daniels SR. Relation of heart rate to left ventricular dimensions in normotensive, normal-weight children, adolescents and adults. Ital Heart J. 2001 Aug;2(8):599-604. PMID: 11577834 [PubMed - indexed for MEDLINE] 18. Devereux RB, Palmieri V, Sharpe N, De Quattro V, Bella JN, de Simone G, Walker JF, Hahn RT, Dahlof B. Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade-based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension: the prospective randomized enalapril study evaluating regression of ventricular enlargement (preserve) trial. Circulation. 2001 Sep 11;104(11):1248-54. PMID: 11551875 [PubMed - indexed for MEDLINE] 19. Galderisi M, Cicala S, De Simone L, Caso P, Petrocelli A, Pietropaolo L, Celentano A, Mininni N, de Divitiis O. Impact of myocardial diastolic dysfunction on coronary flow reserve in hypertensive patients with left ventricular hypertrophy. Ital Heart J. 2001 Sep;2(9):677-84. PMID: 11666096 [PubMed - indexed for MEDLINE] 20. Galderisi M, Vitale G, Lupoli G, Barbieri M, Varricchio G, Carella C, de Divitiis O, Paolisso G. Inverse association between free insulin-like growth factor-1 and isovolumic relaxation in arterial systemic hypertension. Hypertension. 2001 Oct;38(4):840-5. PMID: 11641296 [PubMed - indexed for MEDLINE] 21. Iarussi D, Galderisi M, Ratti G, Tedesco MA, Indolfi P, Casale F, Di Tullio M????ê?????¯?°??????4????????????????????????????????4???????T, de Divitiis O, Iacono A. Left ventricular systolic and diastolic function after anthracycline chemotherapy in childhood. Clin Cardiol. 2001 Oct;24(10):663-9. PMID: 11594412 [PubMed - indexed for MEDLINE] 22. Caso P, Galderisi M, Cicala S, Cioppa C, D'Andrea A, Lagioia G, Liccardo B, Martiniello AR, Mininni N. Association between myocardial right ventricular relaxation time and pulmonary arterial pressure in chronic obstructive lung disease: analysis by pulsed Doppler tissue imaging. J Am Soc Echocardiogr. 2001 Oct;14(10):970-7. PMID: 11593201 [PubMed - indexed for MEDLINE] 23. de Simone G, McClelland R, Gottdiener JS, Celentano A, Kronmal RA, Gardin JM. Relation of hemodynamics and risk factors to ventricular-vascular interactions in the elderly: the Cardiovascular Health Study. J Hypertens. 2001 Oct;19(10):1893-903. PMID: 11593112 [PubMed - indexed for MEDLINE] 24. Celentano A, Crivaro M, Roman MJ, Pietropaolo I, Greco R, Pauciullo P, Lirato C, Devereux RB, de Simone G. Left ventricular geometry and arterial function in hypercholesterolemia. Nutr Metab Cardiovasc Dis. 2001 Oct;11(5):312-9. PMID: 11887428 [PubMed - indexed for MEDLINE] 25. Galderisi M, Tagliamonte MR, D'Errico A, Carella C, Varricchio G, Mondillo S, de Divitiis O, Paolisso G. Independent association of plasma leptin levels and left ventricular isovolumic relaxation in uncomplicated hypertension. Am J Hypertens. 2001 Oct;14(10):1019-24. PMID: 11710780 [PubMed - indexed for MEDLINE] 26. Palmieri V, de Simone G, Arnett DK, Bella JN, Kitzman DW, Oberman A, Hopkins PN, Province MA, Devereux RB. Relation of various degrees of body mass index in patients with systemic hypertension to left ventricular mass, cardiac output, and peripheral resistance (The Hypertension Genetic Epidemiology Network Study). Am J Cardiol. 2001 Nov 15;88(10):1163-8. PMID: 11703964 [PubMed - indexed for MEDLINE] 27, D'Andrea A, Ducceschi V, Caso P, Galderisi M, Mercurio B, Liccardo B, Sarubbi B, Scherillo M, Cotrufo M, Calabro R. ????ê?????¯?°??????4????????????????????????????????4??????? Usefulness of Doppler tissue imaging for the assessment of right and left ventricular myocardial function in patients with dual-chamber pacing. Int J Cardiol. 2001 Nov;81(1):75-83. PMID: 11690667 [PubMed - indexed for MEDLINE] 28. Celentano A, Pietropaolo I, Palmieri V, Di Palma Esposito N, Crivaro M, Cirillo F, Cerbone A, Galderisi M, de Simone G. Inappropriate left ventricular mass and angiotensin converting enzyme gene polymorphism. J Hum Hypertens. 2001 Nov;15(11):811-3. No abstract available. PMID: 11687927 [PubMed - indexed for MEDLINE] 29. Palmieri V, Celentano A, Roman MJ, de Simone G, Lewis MR, Best L, Lee ET, Robbins DC, Howard BV, Devereux RB. Fibrinogen and preclinical echocardiographic target organ damage: the strong heart study. Hypertension. 2001 Nov;38(5):1068-74. PMID: 11711499 [PubMed - indexed for MEDLINE] 30. Galderisi M. Tissue Doppler-derived myocardial diastolic function distinguishes pathologic and physiologic left ventricular hypertrophy. Am J Cardiol. 2001 Dec 1;88(11):1347-8. No abstract available. PMID: 11728373 [PubMed - indexed for MEDLINE] 31. Galderisi M, Severino S, Caso P, Cicala S, Petrocelli A, De Simone L, Mininni N, de Divitiis O. Right ventricular myocardial diastolic dysfunction in different kinds of cardiac hypertrophy: analysis by pulsed Doppler tissue imaging. Ital Heart J. 2001 Dec;2(12):912-20. PMID: 11838339 [PubMed - indexed for MEDLINE] de Simone G, Palmieri V. [Echocardiographic evaluation of ventricular hypertrophy] Recenti Prog Med. 2002 Jan;93(1):58-62. Review. Italian. PMID: 11851002 [PubMed - indexed for MEDLINE] 33. D'Andrea A, Caso P, Severino S, Galderisi M, Sarubbi B, Limongelli G, Cice G, D'Andrea L, Scherillo M, Mininni N, Calabro R. Effects of different training protocols on left ventricular myocardial function in competitive athletes: a Doppler tissue imaging study. Ital Heart J. 2002 Jan;3(1):34-40. PMID: 11899588 [PubMed - indexed for MEDLINE] 34. Galderisi M, Cicala S, Sangiorgi G, Caso P, de Divitiis O. Tissue Doppler-derived postsystolic motion in a patient with left bundle branch block: a sign of myocardial wall asynchrony. Echocardiography. 2002 Jan;19(1):79-81. No abstract available. PMID: 11884261 [PubMed - indexed for MEDLINE] 35. de Simone G, Palmieri V, Bella JN, Celentano A, Hong Y, Oberman A, Kitzman DW, Hopkins PN, Arnett DK, Devereux RB. Association of left ventricular hypertrophy with metabolic risk factors: the HyperGEN study. J Hypertens. 2002 Feb;20(2):323-31. PMID: 11821719 [PubMed - indexed for MEDLINE] 36. Celentano A, Palmieri V, Di Palma Esposito N, Pietropaolo I, Arezzi E, Mureddu GF, de Simone G. Relations of pulse pressure and other components of blood pressure to preclinical echocardiographic abnormalities. J Hypertens. 2002 Mar;20(3):531-7. PMID: 11875322 [PubMed - indexed for MEDLINE] 37. Aurigemma GP, Devereux RB, De Simone G, Roman MJ, O'Grady MJ, Koren M, Alderman M, Laragh J. Myocardial function and geometry in hypertensive subjects with low levels of afterload. Am Heart J. 2002 Mar;143(3):546-51. PMID: 11868064 [PubMed - indexed for MEDLINE] 38. de Simone G, Palmieri V. Left ventricular hypertrophy in hypertension as a predictor of coronary events: relation to geometry. Curr Opin Nephrol Hypertens. 2002 Mar;11(2):215-20. Review. PMID: 11856915 [PubMed - indexed for MEDLINE] 39. Palmieri EA, Benincasa G, Di Rella F, Casaburi C, Monti MG, De Simone G, Chiariotti L, Palombini L, Bruni CB, Sacca L, Cittadini A. Differential expression of TNF-alpha, IL-6, and IGF-1 by graded mechanical stress in normal rat myocardium. Am J Physiol Heart Circ Physiol. 2002 Mar;282(3):H926-34. PMID: 11834488 [PubMed - indexed for MEDLINE] 40. Galderisi M, Severino S, Cicala S, Caso P. The usefulness of pulsed tissue Doppler for the clinical assessment of right ventricular function. Ital Heart J. 2002 Apr;3(4):241-7. PMID: 12025373 [PubMed - indexed for MEDLINE] 41. D'Andrea A, Caso P, Galderisi M, Ducceschi V, Scherillo M, Sarubbi B, Mininni N, Calabro' R. Ventricular interdependence in patients with dual-chamber pacing: a Doppler tissue imaging study. Echocardiography. 2002 May;19(4):289-97. PMID: 12047779 [PubMed - indexed for MEDLINE] 42. Palmieri V, Arnett DK, Roman MJ, Liu JE, Bella JN, Oberman A, Kitzman DW, Hopkins PN, Morgan D, de Simone G, Devereux RB. Appetite suppressants and valvular heart disease in a population-based sample: the HyperGEN study. Am J Med. 2002 Jun 15;112(9):710-5. PMID: 12079711 [PubMed - indexed for MEDLINE] 43. Schillaci G, Pasqualini L, Verdecchia P, Vaudo G, Marchesi S, Porcellati C, de Simone G, Mannarino E. Prognostic significance of left ventricular diastolic dysfunction in essential hypertension. J Am Coll Cardiol. 2002 Jun 19;39(12):2005-11. PMID: 12084601 [PubMed - indexed for MEDLINE] 44. Cicala S, Galderisi M, Caso P, Petrocelli A, D'Errico A, de Divitiis O, Calabro R. Right ventricular diastolic dysfunction in arterial systemic hypertension: analysis by pulsed tissue Doppler. Eur J Echocardiogr. 2002 Jun;3(2):135-42. PMID: 12114098 [PubMed - indexed for MEDLINE] 45. Santarpia L, Pasanisi F, Alfonsi L, Violante G, Tiseo D, De Simone G, Contaldo F. Prevention and treatment of implanted central venous catheter (CVC) - related sepsis: a report after six years of home parenteral nutrition (HPN). Clin Nutr. 2002 Jun;21(3):207-11. PMID: 12127928 [PubMed - indexed for MEDLINE] 46. Caso P, Galderisi M, D'Andrea A, Di Maggio D, De Simone L, Martiniello AR, Mininni N, Calabro R, Sutherland GR. Analysis by pulsed Doppler tissue imaging of ventricular interaction in long-distance competitive swimmers. Am J Cardiol. 2002 Jul 15;90(2):193-7. No abstract available. PMID: 12106860 [PubMed - indexed for MEDLINE] 47. Schillaci G, De Simone G, Reboldi G, Porcellati C, Devereux RB, Verdecchia P. Change in cardiovascular risk profile by echocardiography in low- or medium-risk hypertension. J Hypertens. 2002 Aug;20(8):1519-25. PMID: 12172313 [PubMed - indexed for MEDLINE] 48. Contaldo F, Pasanisi F, Finelli C, de Simone G. Obesity, heart failure and sudden death. Nutr Metab Cardiovasc Dis. 2002 Aug;12(4):190-7. Review. PMID: 12514939 [PubMed - indexed for MEDLINE] 49. de Simone G, Devereux RB. Rationale of echocardiographic assessment of left ventricular wall stress and midwall mechanics in hypertensive heart disease. Eur J Echocardiogr. 2002 Sep;3(3):192-8. Review. PMID: 12144838 [PubMed - indexed for MEDLINE] 50. Vitale G, Ciccarelli A, Caraglia M, Galderisi M, Rossi R, Del Prete S, Abbruzzese A, Lupoli G. Comparison of two provocative tests for calcitonin in medullary thyroid carcinoma: omeprazole vs pentagastrin. Clin Chem. 2002 Sep;48(9):1505-10. PMID: 12194927 [PubMed - indexed for MEDLINE] 51. Galderisi M, Caso P, Cicala S, De Simone L, Barbieri M, Vitale G, de Divitiis O, Paolisso G. Positive association between circulating free insulin-like growth factor-1 levels and coronary flow reserve in arterial systemic hypertension. Am J Hypertens. 2002 Sep;15(9):766-72. PMID: 12219870 [PubMed - indexed for MEDLINE] 52. Gosse P, Dubourg O, Gueret P, De Simone G, Schmieder R, De Leeuw PW, Degaute JP, Garcia Puig J, Karpov Y, Magometschnigg D, Matos L, Amouyel P, Asmar R, Le Heuzey JY, Nieminen M, Dahlof B. Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design. J Hum Hypertens. 2002 Sep;16(9):653-9. PMID: 12214263 [PubMed - indexed for MEDLINE] 53. Vitale G, Galderisi M, Lupoli GA, Celentano A, Pietropaolo I, Parenti N, De Divitiis O, Lupoli G. Left ventricular myocardial impairment in subclinical hypothyroidism assessed by a new ultrasound tool: pulsed tissue Doppler. J Clin Endocrinol Metab. 2002 Sep;87(9):4350-5. PMID: 12213897 [PubMed - indexed for MEDLINE] 54. Galderisi M, Cicala S, Caso P, De Simone L, D'Errico A, Petrocelli A, de Divitiis O. Coronary flow reserve and myocardial diastolic dysfunction in arterial hypertension. Am J Cardiol. 2002 Oct 15;90(8):860-4. PMID: 12372574 [PubMed - indexed for MEDLINE] 55. de Simone G, Verdecchia P, Pede S, Gorini M, Maggioni AP. Prognosis of inappropriate left ventricular mass in hypertension: the MAVI Study. Hypertension. 2002 Oct;40(4):470-6. PMID: 12364349 [PubMed - indexed for MEDLINE] 56. de Simone G, Galderisi M. Quantitation of left ventricular mass and function: balancing evidence with dreams. Ital Heart J. 2002 Oct;3(10):562-70. Review. PMID: 12478813 [PubMed - indexed for MEDLINE] 57. de Simone G. Clinical value of diastolic dysfunction in hypertension. J Hypertens. 2002 Nov;20(11):2309-10; author reply 2310-11. No abstract available. PMID: 12409971 [PubMed - indexed for MEDLINE] 58. Devereux RB, de Simone G, Palmieri V, Oberman A, Hopkins P, Kitzman DW, Rao DC, Arnett DK. Relation of insulin to left ventricular geometry and function in African American and white hypertensive adults: the HyperGEN study. Am J Hypertens. 2002 Dec;15(12):1029-35. PMID: 12460697 [PubMed - indexed for MEDLINE] Chinali M, Romano C, Rocco A, Galderisi M, Betocchi S, De Simone G. Depth variation bias and interaction with gain setting in ultrasonic tissue characterization by integrated backscatter analysis. J Am Soc Echocardiogr. 2003 Jan;16(1):54-60. PMID: 12514635 [PubMed - indexed for MEDLINE] 60. Kozakova M, de Simone G, Morizzo C, Palombo C. Coronary vasodilator capacity and hypertension-induced increase in left ventricular mass. Hypertension. 2003 Feb;41(2):224-9. PMID: 12574086 [PubMed - indexed for MEDLINE] 61. Romano C, Chinali M, Pasanisi F, Greco R, Celentano A, Rocco A, Palmieri V, Signorini A, Contaldo F, de Simone G. Reduced hemodynamic load and cardiac hypotrophy in patients with anorexia nervosa. Am J Clin Nutr. 2003 Feb;77(2):308-12. PMID: 12540387 [PubMed - indexed for MEDLINE] 62. Palmieri V, Celentano A, Roman MJ, de Simone G, Best L, Lewis MR, Robbins DC, Fabsitz RR, Howard BV, Devereux RB; Strong Heart Study. Relation of fibrinogen to cardiovascular events is independent of preclinical cardiovascular disease: the Strong Heart Study. Am Heart J. 2003 Mar;145(3):467-74. PMID: 12660670 [PubMed - indexed for MEDLINE] 63. Guarini P, Scognamiglio G, Cicala S, Galderisi M. [Non-invasive assessment of coronary flow reserve with transthoracic echocardiography: physiopathology, methodology and clinical value] Ital Heart J Suppl. 2003 Mar;4(3):179-88. Review. Italian. PMID: 12784752 [PubMed - indexed for MEDLINE] 64. Vasan RS, Larson MG, Levy D, Galderisi M, Wolf PA, Benjamin EJ; National Heart, Lung, and Blood Institute, National Institutes of Health. Doppler transmitral flow indexes and risk of atrial fibrillation (the Framingham Heart Study). Am J Cardiol. 2003 May 1;91(9):1079-83. PMID: 12714150 [PubMed - indexed for MEDLINE] 65. de Simone G, Devereux RB. What is bright is not always gold. Hypertension. 2003 Jun;41(6):e9-10; author reply e9-10. Epub 2003 Apr 21. No abstract available. PMID: 12707292 [PubMed - indexed for MEDLINE] 66. de Simone G, Devereux RB, Palmieri V, Roman MJ, Celentano A, Welty TK, Fabsitz RR, Contaldo F, Howard BV. Relation of insulin resistance to markers of preclinical cardiovascular disease: the Strong Heart Study. Nutr Metab Cardiovasc Dis. 2003 Jun;13(3):140-7. PMID: 12955795 [PubMed - indexed for MEDLINE] 67. Celentano A, Palmieri V, Arezzi E, Mureddu GF, Sabatella M, Di Minno G, De Simone G. Gender differences in left ventricular chamber and midwall systolic function in normotensive and hypertensive adults. J Hypertens. 2003 Jul;21(7):1415-23. PMID: 12817192 [PubMed - indexed for MEDLINE] 68. Verdecchia P, Sleight P, Avanzini F, de Simone G, Pede S, Perticone F, Schillaci G, Vanuzzo D, Angeli F, Reboldi GP, Maggioni AP. Hypertrophy at ECG and its regression during treatment survey (HEART survey). Rationale, design and baseline characteristics of patients. Ital Heart J. 2003 Jul;4(7):479-83. PMID: 14558300 [PubMed - indexed for MEDLINE] 69. D'Errico A, Galderisi M, Pollio G, Catalano L, Rotoli B, de Divitiis O. A case of hypereosinophilic cardiomyopathy: additional value of the myocardial contrast agent SonoVue for the differential diagnosis of a cardiac mass. Ital Heart J. 2003 Aug;4(8):571-4. PMID: 14564987 [PubMed - indexed for MEDLINE] 70. de Simone G. Left ventricular geometry and hypotension in end-stage renal disease: a mechanical perspective. J Am Soc Nephrol. 2003 Oct;14(10):2421-7. Review. PMID: 14514719 [PubMed - indexed for MEDLINE] 71. Citro R, Galderisi M, Guarini P, Cicala S, Mattioli D, Bianco A, de Divitiis O, Gregorio G. Left bundle branch block with and without coronary artery disease: which value for a tissue Doppler-derived post-systolic motion? Ital Heart J. 2003 Oct;4(10):706-12. PMID: 14664284 [PubMed - indexed for MEDLINE] 72. Galderisi M, de Simone G, Cicala S, De Simone L, D'Errico A, Caso P, de Divitiis O. Coronary flow reserve in hypertensive patients with appropriate or inappropriate left ventricular mass. J Hypertens. 2003 Nov;21(11):2183-8. PMID: 14597863 [PubMed - indexed for MEDLINE] 73. Verdecchia P, Angeli F, Borgioni C, Gattobigio R, de Simone G, Devereux RB, Porcellati C. Changes in cardiovascular risk by reduction of left ventricular mass in hypertension: a meta-analysis. Am J Hypertens. 2003 Nov;16(11 Pt 1):895-9. PMID: 14573325 [PubMed - indexed for MEDLINE] 74. de Simone G, Devereux RB, Palmieri V, Bella JN, Oberman A, Kitzman DW, Hopkins PN, Rao DC, Arnett DK; HyperGEN Study. Influence of fat-free mass on detection of appropriateness of left ventricular mass: the HyperGEN Study. J Hypertens. 2003 Sep;21(9):1747-52. PMID: 12923408 [PubMed - indexed for MEDLINE] Chinali M, Devereux RB, Howard BV, Roman MJ, Bella JN, Liu JE, Resnick HE, Lee ET, Best LG, de Simone G. Comparison of cardiac structure and function in American Indians with and without the metabolic syndrome (the Strong Heart Study). Am J Cardiol. 2004 Jan 1;93(1):40-4. PMID: 14697463 [PubMed - indexed for MEDLINE] 76. de Simone G, Grassi G. Fat is bad: even in thin people? J Hypertens. 2004 Jan;22(1):35-7. No abstract available. PMID: 15106790 [PubMed - indexed for MEDLINE] 77. Galderisi M, Dini FL, Temporelli PL, Colonna P, de Simone G. [Doppler echocardiography for the assessment of left ventricular diastolic function: methodology, clinical and prognostic value] Ital Heart J Suppl. 2004 Feb;5(2):86-97. Review. Italian. PMID: 15080528 [PubMed - indexed for MEDLINE] 78. Vitale G, Galderisi M, Pivonello R, Spinelli L, Ciccarelli A, de Divitiis O, Lombardi G, Colao A. Prevalence and determinants of left ventricular hypertrophy in acromegaly: impact of different methods of indexing left ventricular mass. Clin Endocrinol (Oxf). 2004 Mar;60(3):343-9. PMID: 15009000 [PubMed - indexed for MEDLINE] 79. de Simone G. Concentric or eccentric hypertrophy: how clinically relevant is the difference? Hypertension. 2004 Apr;43(4):714-5. Epub 2004 Feb 23. No abstract available. PMID: 14981062 [PubMed - indexed for MEDLINE] 80. Agricola E, Galderisi M, Oppizzi M, Schinkel AF, Maisano F, De Bonis M, Margonato A, Maseri A, Alfieri O. Pulsed tissue Doppler imaging detects early myocardial dysfunction in asymptomatic patients with severe mitral regurgitation. Heart. 2004 Apr;90(4):406-10. PMID: 15020516 [PubMed - indexed for MEDLINE] 81. Galderisi M, Vitale G, D'Errico A, Lupoli GA, Ciccarelli A, Cicala S, Pardo M, Lupoli G, de Divitiis O. Usefulness of pulsed tissue Doppler for the assessment of left ventricular myocardial function in overt hypothyroidism. Ital Heart J. 2004 Apr;5(4):257-64. PMID: 15185883 [PubMed - indexed for MEDLINE] 82. Olsen MH, Wachtell K, de Simone G, Palmieri V, Dige-Petersen H, Devereux RB, Ibsen H, Rokkedal J. Is inappropriate left ventricular mass related to neurohormonal factors and/or arterial changes in hypertension? A LIFE substudy. J Hum Hypertens. 2004 Jun;18(6):437-43. PMID: 15014540 [PubMed - indexed for MEDLINE] 83. Galderisi M, Mondillo S. Tissue Doppler and cardiac resynchronisation therapy: a new challenge for the optimal choice of candidates. Eur Heart J. 2004 Aug;25(15):1363; author reply 1363-4. No abstract available. PMID: 15288163 [PubMed - indexed for MEDLINE] 84. Cioffi G, Mureddu GF, Stefenelli C, de Simone G. Relationship between left ventricular geometry and left atrial size and function in patients with systemic hypertension. J Hypertens. 2004 Aug;22(8):1589-96. PMID: 15257183 [PubMed - indexed for MEDLINE] 85. de Simone G, Kitzman DW, Palmieri V, Liu JE, Oberman A, Hopkins PN, Bella JN, Rao DC, Arnett DK, Devereux RB. Association of inappropriate left ventricular mass with systolic and diastolic dysfunction: the HyperGEN study. Am J Hypertens. 2004 Sep;17(9):828-33. PMID: 15363827 [PubMed - indexed for MEDLINE] 86. Gosse P, de Simone G, Dubourg O, Gueret P, Schmieder R. Serial echocardiographic assessment of left ventricular mass: how blinded should readers be? J Hypertens. 2004 Sep;22(9):1813-8. PMID: 15311111 [PubMed - indexed for MEDLINE] 87. Dini FL, Galderisi M, Mondillo S, De Tommasi SM. [The right ventricle: role of Doppler echocardiography in clinical practice] Ital Heart J Suppl. 2004 Oct;5(10):757-69. Review. Italian. PMID: 15615347 [PubMed - indexed for MEDLINE] 88. Galderisi M, Cicala S, D'Errico A, de Divitiis O, de Simone G. Nebivolol improves coronary flow reserve in hypertensive patients without coronary heart disease. J Hypertens. 2004 Nov;22(11):2201-8. PMID: 15480106 [PubMed - indexed for MEDLINE] 89. Innelli P, Galderisi M. Which role of echocardiography to predict systemic embolism in dilated cardiomyopathy? Am J Cardiol. 2004 Dec 1;94(11):1479-80. No abstract available. PMID: 15566936 [PubMed - indexed for MEDLINE] 90. Cicala S, Galderisi M, Guarini P, D'Errico A, Innelli P, Pardo M, Scognamiglio G, de Divitiis O. Transthoracic coronary flow reserve and dobutamine derived myocardial function: a 6-month evaluation after successful coronary angioplasty. Cardiovasc Ultrasound. 2004 Dec 6;2(1):26. PMID: 15581428 [PubMed - in process] 91. Rotoli B, Catalano L, Galderisi M, Luciano L, Pollio G, Guerriero A, D'Errico A, Mecucci C, La Starza R, Frigeri F, Di Francia R, Pinto A. Rapid reversion of Loeffler's endocarditis by imatinib in early stage clonal hypereosinophilic syndrome. Leuk Lymphoma. 2004 Dec;45(12):2503-7. PMID: 15621768 [PubMed - indexed for MEDLINE] 0792 [PubMed - in process] 114. de Simone G. State of the heart in the metabolic syndrome. Nutr Metab Cardiovasc Dis. 2005 Aug;15(4):239-41. No abstract available. PMID: 16054546 [PubMed - in process] 115. Agricola E, Galderisi M, Oppizzi M, Melisurgo G, Airoldi F, Margonato A. Doppler tissue imaging: a reliable method for estimation of left ventricular filling pressure in patients with mitral regurgitation. Am Heart J. 2005 Sep;150(3):610-5. PMID: 16169349 [PubMed - in process] 116. Tang W, Arnett DK, Devereux RB, Panagiotou D, Province MA, Miller MB, de Simone G, Gu C, Ferrell RE. Identification of a novel 5-base pair deletion in calcineurin B (PPP3R1) promoter region and its association with left ventricular hypertrophy. Am Heart J. 2005 Oct;150(4):845-51. PMID: 16209992 [PubMed - in process] 117. de Simone G, Devereux RB, Maggioni AP, Gorini M, de Divitiis O, Verdecchia P. Different Normalizations for Body Size and Population Attributable Risk of Left Ventricular Hypertrophy: The MAVI Study. Am J Hypertens. 2005 Oct;18(10):1288-93. PMID: 16202850 [PubMed - in process] 2002.21 February, Workshop on "Role of echocardiography in the diagnosis of diastolic heart failure". 2002.11-12 April, Workshop on: " Echocardiographic evaluation of left ventricular hypertrophy" 2002. 25 June. Lecture: Coronary flow reserrve: from research to clinical practice. Dr. Paolo Voci, University Tor Vergata, Roma 2002. 1-5 July. Learning Basic Echocardiography. ECM credits: 29 2002. 14 October. Cardiology Grand-round. Diastolic heart failure. Dr. Micheal Zile, University of South-Carolina. 2002. 21-22 Novembre: Workshop su: " Valutazione ecocardiografica delle ipertrofie ventricolari" in collaborazione con L'Accademia Nazionale di Medicina. ECM: 12. 2003. 27-30 Gennaio. Corso Basic di Ecocardiografia. crediti ECM: 27 2003. 4 Febbraio. Seminario di Ecocardiografia: Il rischio cardiovascolare nel laboratorio eco. Dr. Eugenio Picano. CNR, Pisa 2003. 11 Marzo. Ecocardiografia: Come si studia la riserva di flusso coronarico. crediti ECM: 5 2003. 9-10 Maggio. Ecocardiografia: Come si studia la riserva di flusso coronarico. crediti ECM: 12 2003. 19-23 Maggio. MASTER IPERTENSIONE ARTERIOSA: ANNULLATO 2003. 30 Giugno-4 Luglio. Corso Basic di Echocardiografia. crediti ECM: da richiedere 2003. 9-10 Settembre. Echocardiografia: L'uso del TD nella pratica clinica. crediti ECM: da richiedere 2003. 27-28 Novembre. Valutazione ecocardiografica delle ipertrofie ventricolari. crediti ECM: da richiedere Segreteria scientifica: dr. Maurizio Galderisi tel. 081/7462145-7462013 e-mail: mgalderi@unina.it 2004/13 GENNAIO. Corso teorico pratico su Doppler tissutale. ECM:10 2004/16 MARZO . La riserva di flusso Coronarica con metodica ultrasonora:attualitàe prospettive. ECM: 4 2004/26 APRILE. L'esame ecocardiografico Doppler transtoracico nella pratica clinica. ECM: 33 2004/28 MAGGIO. Il microcircolo coronarico nell'infarto miocardico: Ruolo dell'ecocontrastografia miocardica. ECM:2 2004/8 SETTEMBRE. Il Doppler tissutale nella cardiologia clinica: corso teorico-pratico. ECM:16 2004/9 OTTOBRE. Potenzialitàe prospettive nella diagnosi precoce di scompenso cardiaco. ECM:4 2004/NOVEMBRE 29 Potenzialitàed applicazioni del Doppler tissutale nella cardiologica clinica. ECM:17 2005/MARZO 15 La riserva di flusso coronarica con metodica ultrasonora. CreditiECM:5 2005/APRILE 26 Potenzialità ed applicazioni del Doppler tissutale nella cardiologia clinica: corso teorico-pratico. Crediti ECM:14 2005/MAGGIO 24-26 Corso base in ecocardiografia transtoracica. Crediti ECM: 33 2005/SETTEMBRE 20-21. Corso teorico-pratico: Le nuove tecnologie ecocardiografiche nella gestione del paziente con scompenso cardiaco: potenzialità ed applicazioni cliniche. Crediti ECM: 16